Effective regional connectivity calls for a vibrant relationship between economic and social infrastructure, on the one hand, and an underlying enabling policy framework for the financing and development of sustainable, appropriate infrastructure, on the other. In a rapidly changing, complex world where crises occur with regularity, there are weighty uncertainties that shape future markets, government and governance, and social and economic values. Anticipatory governance allows for the evaluation of potential activities that can help to shape the future in a complex environment, such as the SADC infrastructure landscape. The operationalisation of anticipatory governance can make a world of difference, allowing key stakeholders (including governments and their partners) to reflect on various early signals and barely recognisable inputs, thereby detecting and exploring unexpected complex emerging disruptors well before the pressing need to execute necessary changes. In SADC, transformative infrastructure can stimulate economic growth, delivering employment and an economically, socially and environmentally sustainable recovery from the COVID-19 crisis. Infrastructure investment has a high potential multiplier effect and a long-term impact on raising economic wellbeing. The Global Infrastructure Hub has found that the fiscal multiplier of public investment has generally been higher in the contractionary phase of the business cycle, particularly when interest rates are low. Through this current recessionary phase, the economic scene is set for greater government investment in infrastructure. The question is how to achieve transformative infrastructure outcomes in the region, now.