UN 2.0 considers the kinds of enlightened global leadership and vision, norms, tools, institutions, and ethic of civic engagement required to better deal with pressing global challenges, from avoiding runaway climate change to preventing atrocities and reducing the disruptive potential of novel technologies. Drawing parallels to the 1944 Dumbarton Oaks conference that, in the midst of World War II and on the heels of the Great Depression, laid the groundwork for the successful 1945 San Francisco conference that founded the United Nations, the report argues for this September’s UN75 Summit and Declaration to lay the foundations for further innovating and strengthening global governance in the coming two-to-three critical years. In presenting a bold yet practical roadmap for global renewal, UN 2.0 stresses the need for international organizations, starting with the United Nations, to harness creatively the ideas, networks, and capabilities of governments, civil society, and the private sector for effective global problem-solving.